Monthly Archives: November 2015

Research: “Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model for Autism Spectrum Disorder”

Currently, the etiology of autism spectrum disorder (ASD) is unclear, and therefore no appropriate “cure” exists. Gene mutations have been found to play a role in the onset of ASD. Mouse models are useful and reliable in studying the cause of disorders … Continue reading

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Research: “Genetic Animal Models for Autism Spectrum Disorder”

Recent advances in research indicate that the development of autism spectrum disorder (ASD) has a strong genetic component. Being able to identify the specific genetic makeup for ASD would allow for better understanding of the disorder and for the development … Continue reading

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Research: “Altered striatal synaptic function and abnormal behaviour in Shank3 Exon4-9 deletion mouse model of autism”

People with a mutated SHANK3 gene often present with delayed or impaired speech, as well as Obsessive Compulsive Disorder-like behaviors; additionally, the SHANK3 mutation is present in some cases of Autism Spectrum Disorder (ASD).The SHANK3 gene assists in neurotransmitter connection, … Continue reading

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