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Monthly Archives: July 2015
Research: “Cerebellar Associative Sensory Learning Defects in five Mouse Autism Models”
Atypical sensory development is found in both human patients and SHANK3 knockout mice. It is known that genes associated with ASD (in this case SHANK3) can shape and affect cerebellum circuit functions, and that changes in the cerebellum affect behavior … Continue reading
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Research: “Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission & Behavioral Deficits”
SHANK3 is a gene that assists neurotransmitter connection, synapse formation, and dendrite spine maturation. The autism-associated insertion mutation (InsG) of SHANK3 exon 21 was found in two brothers with clinically identical cases of autism spectrum disorder (ASD), but not in … Continue reading
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